Heading 1
77. Gan, X.-c.;† Zhang, B.;† Dao, N.;† Bi, C.; Pokle, M.; Kan, L.; Collins, M. R.; Tyrol, C. C.; Bolduc, P. N.; Nicastri, M.; Kawamata, Y.; Baran, P. S.; Shenvi, R. A. Carbon Quaternization of Redox Active Esters and Olefins via Decarboxylative Coupling. Science (accepted).
ChemRxiv 10.26434/chemrxiv-2023-7vb8x †co-first authors
76. van der Puyl-Lovett;† V. A.; Gan, X.-c.;† Kong, L.;† Shenvi, R. A. Alkene hydrobenzylation by a single catalyst that mediates iterative outer-sphere steps. J. Am. Chem. Soc. 2024, 146, 2351.
ChemRxiv 10.26434/chemrxiv-2023-zw9c2 2023, †co-first authors.
75. Kotesova, S.; Shenvi, R. A. Inner- and outer-sphere cross-couplings for high Fsp3 fragments in natural product space. Acc. Chem. Res. 2023, 56, 3089.
74. Ting, S.;† Snelson, D.;† Huffman, T. R.; Kuroo, A.; Sato, R.; Shenvi, R. A. Synthesis of (–)-cotylenol, a 14-3-3 molecular glue component. J. Am. Chem. Soc. 2023, 145, 20634. †co-first authors
73. Gan, X.-c.;§ Kotesova, S.;§ Castanedo, A.; Green, S. A.; Møller, S. L. B.; Shenvi, R. A. Iron-catalyzed hydrobenzylation: stereoselective synthesis of (–)-eugenial C. J. Am. Chem. Soc. 2023, 145, 15714. §co-first authors
71. Shenvi, R. A. Early Childhood Care as an Academic: The Slow Burn. Angew. Chem. Int. Ed., 2023, in press [Ihr verborgenes Leben (Their Hidden Lives) Essay Series].
69. Woo, S.; Landwehr, E.; Shenvi, R. A. Synthesis of psychotropic alkaloids from Galbulimima Tetrahedron 2022, 126, 133064. [In celebration of the 65th anniversary of Tetrahedron Publications]
68. Shevick, S. L.; Freeman, S.; Tong, G.; Russo, R. J.; Bohn, L. M.; Shenvi, R. A. Asymmetric syntheses of (+)- and (–)-collybolide enable re-evaluation of kappa-opioid receptor agonism ACS Cent. Sci., 2022, 8, 948–954. DOI: https://doi.org/10.1021/acscentsci.2c00442.
ChemRxiv DOI: 10.26434/chemrxiv-2021-rtxqf
ChemRxiv DOI: 10.26434/chemrxiv.8263415.v1
60. Shevick, S. L.; Wilson, C. V.; Kotesova, S.; Kim, D.; Holland, P. L.; Shenvi, R. A. Catalytic hydrogen atom transfer to alkenes: a roadmap for metal hydrides and radicals. Chem. Sci. 2020, 12401–12422.
59. Demoret, R. M.; Baker, M. A.; Ohtawa, M.; Chen, S.; Lam, C.-C.; Khom, S.; Roberto, M.; Forli, S.; Houk, K.; Shenvi, R. A. Synthetic, Mechanistic and Biological Interrogation of Ginkgo biloba Chemical Space en route to (–)-Bilobalide. J. Am. Chem. Soc. 2020, 142, 18599–18618.ChemRxiv DOI: 10.26434/ chemrxiv.12132939.v2
57. Crossley, S. W. M.; Tong, G.; Lambrecht, M. J.; Burdge, H. E.; Shenvi, R. A. Total Synthesis of (–)-Picrotoxinin J. Am. Chem. Soc. 2020, 142, 11376–11381.
51. Baker, M.; Demoret, R.; Ohtawa, M.; Shenvi, R. A. Concise Asymmetric Synthesis of (–)-Bilobalide Nature 2019, 575, 643–646. DOI: 10.1038/s41586-019-1690-5. ChemRxiv DOI: 10.26434/chemrxiv.8202053.v1 Featured in Org. Chem. Highlights
44. Shevick, S. L.; Obradors, C.; Shenvi, R. A. Mechanistic Interrogation of Co/Ni-Dual Catalyzed Hydroarylation J. Am. Chem. Soc. 2018,140, 12056–12068.
43. Green, S. A.; Vásquez-Céspedes, S.; Shenvi, R. A. Iron-Nickel Dual-Catalysis: A New Engine for Olefin Functionalization. J. Am. Chem. Soc. 2018, 140, 11317–11324
-
Highlighted by Tien Ngyuen in C&EN, Sept. 1 2017.
-
See article on SlashGear by Brittany Rosen, Sept. 11, 2017
-
See article on Gizmodo by Ryan Mandalbaum, Sept. 12, 2017
-
See article on Geek by Daniel Starkey, Sept. 12, 2017
-
See article on Wired by Matthew Simon, Jan. 8, 2018
20. Crossley, S. W. M.; Barabé, F.; Shenvi, R. A. Simple, Chemoselective, Catalytic Olefin Isomerization. J. Am. Chem. Soc. 2014, 136, 16788.
17. Pronin, S. V.; Reiher, C. A.; Shenvi, R. A. Stereoinversion of tertiary alcohols to tertiary alkyl isonitriles and amines. Nature. 2013, 501, 195-199.
-
Highlighted by Bethany Halford in C&EN 2013, 91, 8.
-
Highlighted by Stephen Davey in Nature Chemistry 2013, 5, 808.
-
Highlighted by A. Räder and K. Tiefenbacher: Angew. Chem. Int. Ed. 2013, 52, 2.
-
Selected for highlight in C&EN: “2013’s Notable Advances” 2013, 91, 15.
• In top ten most accessed articles of J. Am. Chem. Soc. for January 2012.
• Highlighted in Nature Chemistry, May 2012.
Postdoctoral, Graduate and Undergraduate
12. Shi, J.; Manolikakes; G. Yeh, C.-H.; Guerrero, C. A.; Shenvi, R. A.; Shigehisa, Hiroki; Baran, P. S. Scalable Synthesis of Cortistatin A and Related Structures. J. Am. Chem. Soc. 2011, 133, 8014-8027.
11. Shenvi, R. A.; Corey, E. J. Synthetic Access to Bent Polycycles by Cation-Pi Cyclization. Org. Lett. 2010, 12, 3548-3551.
10. Shenvi, R. A.; Corey, E. J. A Short and Efficient Synthesis of (–)-7-Methylomuralide, a Potent Proteasome Inhibitor. J. Am. Chem. Soc., 2009, 131, 5746-5747.
9. Shi, J.; Shigehisa, H.; Guerrero, C. A.; Shenvi, R. A.; Li, R. A.; Baran, P. S. Stereodivergent Synthesis of 17-α and 17-β-Aryl Steroids: Application and Biological Evaluation of D-Ring Cortistatin Analogues. Angew. Chem. Int. Ed. 2009, 48, 4328-4331.
8. Shenvi, R. A.; O’Malley, D. P.; Baran, P. S. Chemoselectivity: The Mother of Invention in Total Synthesis. Acc. Chem. Res. 2009, 42, 530-541.
7. Shenvi, R. A. (2008). Pure and Applied Science in the Chemical Syntheses of Marine Alkaloids Chartelline C and Cortistatin A. Ph.D. Thesis, The Scripps Research Institute, 2008.
6. Shenvi, R. A.; Guerrero, C. A.; Shi, J.; Li, C.-C.; Baran, P. S. Synthesis of (+)-Cortistatin A. J. Am. Chem. Soc. 2008, 130, 7241-7243.
5. Baran, P. S.; Shenvi, R. A. Total Synthesis of (±)-Chartelline C. J. Am. Chem. Soc. 2006, 128, 14028-14029.
4. Baran, P. S.; Shenvi, R. A.; Nguyen, S. A. One-Step Synthesis of 4,5-Disubstituted Pyrimidines Using Commercially Available and Inexpensive Reagents. Heterocycles. 2006, 70, 581-586.
3. Baran, P. S.; Shenvi, R. A., Mitsos, C. A. A Remarkable Ring Contraction En Route to the Chartelline Alkaloids. Angew. Chem. Int. Ed. 2005, 44, 3714-3717.
2. Shenvi, R. A.; Funk, R. L. (2003). An approach to the synthesis of the potent antimicrotubule agent ottelione (RPR112378). B.S. Thesis, Pennsylvania State University, 2003.
1. Ababou, A.; Shenvi, R. A.; Desjarlais, J. R. Long-Range Effects on Calcium Binding and Conformational Change in the N-Domain of Calmodulin. Biochemistry 2001, 40, 12719-12726.