Beckman Center for Chemical Sciences

10550 N. Torrey Pines Road

La Jolla, CA   92037

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56. Shevick, S. L.; Baker, M. A.; Shenvi, R. A. Alkene Hydroarylation by Co/Ni Dual Catalysis, Cell: Trends in Chemistry2019 

DOI:10.1016/j.trechm.2019.06.003

55. Matos, J. L. M.; Green, S. A.; Shenvi, R. A. Markovnikov Functionalization by Hydrogen Atom Transfer, Organic Reactions, in press.

52. Huffman, B. J.; Chen, S.; Schwarz, J. L; Plata, R. E.; Chin, E.; Houk, K. N.; Lairson, L. L.; Shenvi, R. A. Electronic Complementarity Permits Hindered Butenolide Heterodimerization and Discovery of Novel cGAS/STING Pathway Antagonists, Nature Chem. 2019, accepted.

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  • #1 Most Viewed Article on ChemRxiv, Aug-Dec 2017.

  • Highlighted by Tien Ngyuen in C&EN, Sept. 1 2017.

  • See article on SlashGear by Brittany Rosen, Sept. 11, 2017

  • See article on Gizmodo by Ryan Mandalbaum, Sept. 12, 2017

  • See article on Geek by Daniel Starkey, Sept. 12, 2017

  • See article on Wired by Matthew Simon, Jan. 8, 2018

  • Featured by TCI Chemicals

  • Highlighted by Bethany Halford in C&EN 2013, 91, 8.

  • Highlighted by Stephen Davey in Nature Chemistry 2013, 5, 808.

  • Highlighted by A. Räder and K. Tiefenbacher: Angew. Chem. Int. Ed. 2013, 52, 2.

  • Selected for highlight in C&EN: “2013’s Notable Advances” 2013, 91, 15.

• In top ten most accessed articles of J. Am. Chem. Soc. for January 2012.

• Highlighted in Nature Chemistry, May 2012.

Postdoctoral, Graduate and Undergraduate

12. Shi, J.; Manolikakes; G. Yeh, C.-H.; Guerrero, C. A.; Shenvi, R. A.; Shigehisa, Hiroki; Baran, P. S. Scalable Synthesis of Cortistatin A and Related Structures. J. Am. Chem. Soc. 2011133, 8014-8027.

11. Shenvi, R. A.; Corey, E. J. Synthetic Access to Bent Polycycles by Cation-Pi Cyclization. Org. Lett. 201012, 3548-3551.

10. Shenvi, R. A.; Corey, E. J. A Short and Efficient Synthesis of (–)-7-Methylomuralide, a Potent Proteasome Inhibitor. J. Am. Chem. Soc.2009131, 5746-5747.

9. Shi, J.; Shigehisa, H.; Guerrero, C. A.; Shenvi, R. A.; Li, R. A.; Baran, P. S. Stereodivergent Synthesis of 17-α and 17-β-Aryl Steroids: Application and Biological Evaluation of D-Ring Cortistatin Analogues. Angew. Chem. Int. Ed. 200948, 4328-4331.

8. Shenvi, R. A.; O’Malley, D. P.; Baran, P. S. Chemoselectivity: The Mother of Invention in Total Synthesis. Acc. Chem. Res. 2009, 42, 530-541.

7. Shenvi, R. A. (2008). Pure and Applied Science in the Chemical Syntheses of Marine Alkaloids Chartelline C and Cortistatin A. Ph.D. Thesis, The Scripps Research Institute, 2008.

6. Shenvi, R. A.; Guerrero, C. A.; Shi, J.; Li, C.-C.; Baran, P. S. Synthesis of (+)-Cortistatin A. J. Am. Chem. Soc. 2008130, 7241-7243.

5. Baran, P. S.; Shenvi, R. A. Total Synthesis of (±)-Chartelline C. J. Am. Chem. Soc. 2006128, 14028-14029.

4. Baran, P. S.; Shenvi, R. A.; Nguyen, S. A. One-Step Synthesis of 4,5-Disubstituted Pyrimidines Using Commercially Available and Inexpensive Reagents. Heterocycles. 200670, 581-586.

3. Baran, P. S.; Shenvi, R. A., Mitsos, C. A. A Remarkable Ring Contraction En Route to the Chartelline Alkaloids. Angew. Chem. Int. Ed. 200544, 3714-3717.

2. Shenvi, R. A.; Funk, R. L. (2003). An approach to the synthesis of the potent antimicrotubule agent ottelione (RPR112378). B.S. Thesis, Pennsylvania State University, 2003.

1. Ababou, A.; Shenvi, R. A.; Desjarlais, J. R. Long-Range Effects on Calcium Binding and Conformational Change in the N-Domain of Calmodulin. Biochemistry 200140, 12719-12726.